HYBRID EVENT: You can participate in person at Rome, Italy or Virtually from your home or work.
HYBRID EVENT
September 16-18, 2024 | Rome, Italy
GPMB 2024

Pratima Mathad

Pratima Mathad, Speaker at Plant Science Conferences
Pratima Mathad
Gulbarga University, India
Title : Systematic evaluation of phytochemical and neuropharmacological activities on central nervous system of mice model by different solvent extracts of wild plant Digeria muricata (L.) mart

Abstract:

The present investigation is undertaken to evaluate the phytochemical and neuropharmacological activities in a wild edible medicinal plant Digera muricata (L.) mart., which belongs to Amarathaceae. The phytochemical analysis was found positive for phenols, flavonoids, glycosides, tannins and terpenoids whereas, minimal for saponins. The whole plant was used to analyze the free radical scavenging and antioxidant activities in different solvent extracts of the plant using successive Soxhlet extractor. The activities were assessed by Dpph, ascorbic acid content, reducing property, Pod and Sod. All the extracts showed promising results towards free radical scavenging and antioxidative properties. The maximum activity was recorded in methanol and the minimal, in hexane plant extracts.

The study further reports the neuropharmacological activities on the Central Nervous System (Cns) of Swiss albino mice using aqueous extracts of Digeria Muricata. The aqueous extracts of the plant were tested for neuropharmacological activities such as acute toxicity, spontaneous motor activity, exploratory behavioral pattern, marble burying and tail suspension. The acute toxicity induced mice were administered with doses of plant extracts in the range 50-200 mg/kg of body weight using different standards e.g. 3 mg of chlorpromazine or imipramine/kg and 4 mg of diazepam/kg. The plant dosage with 150 mg/kg was found to produce a profound increase in all the behavioral activities. It also showed a marked antidepressant effect with neuroleptic properties as evidenced by a significant enhancement in all the central nervous system behavioral experiments. The results thus reveal that the wild plant Digeria Muricata has prominent medicinal value exhibiting both antioxidant and anti depressant properties.

Audience Takeaway:

  • The audience will learn from the presentation the medicinal values of the plant species
  • The presentation will help to explore plants in the local habitats for medicinal properties.
  • The research would definitely influence other faculty to further expand their research works.

Biography:

Dr. Pratima Mathad studied Botany at the University of Mysore, Mysuru, India and graduated as M Sc in Botany in 1988. She has completed her M Phil and Ph D in Botany from Gulbarga University, Kalaburagi, India. She was subsequently appointed as Lecturer at the Department of Postgraduate Studies and Research in Botany, Gulbarga University and presently she is serving as a Senior Professor of Botany in the same institution. She has shouldered many administrative and academic responsibilities working on diverse areas of plant sciences and has published more than 75 research articles in various scientific journals.

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