Title : Volatile components of centaurea scleroiepis boiss and its in-vitro biological activities
Abstract:
Centaurea is an important and widespread genus in Asteraceae. There are 194 species in Turkey of which 118 them are endemic. There are various studies on essential oils and fatty acids of the genus Centaurea. The genus Centaurea is recognized as having significant potential in both conventional systems and drug development. It has traditionally been used for asthma, abdominal pain, headache, hemorrhoids, diarrhea, rheumatoid arthritis, stomach, antipyretic, astringent and antibacterial uses. Centaurea genus contains intensely phenolic structures and flavonoids. In addition to these, sesquiterpene lactones, lignans, alkaloids are rarely seen. It shows a wide variety of biological activities with its rich chemical content. In studies with Centaurea species, antioxidant, antimicrobial, antiproliferative, hepatoprotective, anti-inflammatory, antiulcerogenic, antiplasmodial and enzyme inhibitor activities were observed. Free radicals can alter lipids, proteins, and DNA and trigger many diseases. However, outside help is required to scavenge free radicals if the defense defense system is insufficient. Antioxidants protect the body from oxidative stress by scavenging free radicals. In this study, the essential oil of Centaurea scleroiepis Boiss. collected from Batman, Turkey was obtained by hydrodistillation using a Clevenger-type apparatus. GC and GC/MS analyzes of the essential oil from were determined the identification of 75 components representing 87.63% of the oil. Major 9.99% 2-penthanethiol; 9.07% Trimethylamine oxide; 4.24% Benzeneacetaldehyde; 5.72% Cyclohexen-1-one was detected. It has been determined that the major components of this endemic species, which is very similar to Centaurea kurdica, are different. DPPH, ABTS and superoxide scavenging activity of methanol extract and essential oil were evaluated. The DPPH, ABTS and superoxide radical scavenging activity of the essential oil were determined as 100.02, 78.98, 16.54, respectively.
What will audience learn from your presentation?
- Phytochemistry of an endemic species of Centaurea
- Volatile components of Centaurea scleroiepis Boiss.
- The content and in vitro activities of the unstudied Centaurea species will be evaluated.
