HYBRID EVENT: You can participate in person at Rome, Italy or Virtually from your home or work.
September 16-18, 2024 | Rome, Italy
GPMB 2018

Tongda Xu

Tongda Xu, Speaker at Botany Conference
Fujian Agricultural and Forestry University, China
Title : TMK-mediated transcriptional auxin signaling in regulating plant development


Auxin plays diverse and profound roles in plants, regulating essentially all aspects of plant growth and development, but how auxin achieves the functional diversity and specificity is largely unknown.Multiple auxin signaling integrated totriggerdistinctive auxin responses according to its concentration, which is essential for differential growth such as apical hook development. We showed that high auxin at concave side of apical hook stimulates the C-terminus cleavage and cytosolic translocation of Trans-Membrane Kinase (TMK), which phosphorylates noncanonical IAAs. Surprisingly, in contrast to previous report that auxin degraded AUX/IAA proteins through TIR1/ AFB receptor to regulate gene expression, here we found that non-canonical IAAsproteins were stabilized by high auxin through TMKcleavage to negatively regulate gene expression and inhibit growth. This finding demonstrated a TIR independent transcriptional auxin signalingthat regulate growth inhibition in response to high auxin.


Tongda Xu got B.S degree in Peking University in 2003, Ph.D in University of California Riverside in 2010. In 2011, Xu become Young Investigator and setup the lab in TemasekLifescience Laboratory Ltdin Singapore; In 2014, Xu become Principal Investigator in Shanghai Center for Plant Stress Biology in China Academy of Sciences. Xu’s lab is working on ABP/TMK based auxin sensing complex on plasma membrane, and aimed to investigate the molecular mechanism about how ABP/TMK regulate auxin dependent cell expansion, cell division and cell differentiation. In the meanwhile, his lab is also studying how auxin participates in other signaling pathways such as stress responses.